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EMD-
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TitleCryo EM structure of System XC-
AuthorsParker JL, Deme JC
MethodSingle Particle(Reported Resolution 3.4 Å)PDB:7p9v
EMDB image
Primary CitationMolecular basis for redox control by the human cystine/glutamate antiporter system xc . Parker JL, Deme JC, Kolokouris D, Kuteyi G, Biggin PC, Lea SM, Newstead S Nat Commun (2021) PubMed DOI show all entries for this citation
Funding SourceMedical Research Council (MRC, United Kingdom), Engineering and Physical Sciences Research Council, Wolfson Foundation, Wellcome Trust
StatusDepositedReleasedLast Update
REL2021-07-282021-11-172024-11-13

Name: System XC-SpecimenType: particle MW: 0.126 MDa pH: 7.5

Component Typescomplex
Component Names

System XC-

Molecular Typesprotein
Molecule Names
  • 4F2 cell-surface antigen heavy chain
  • Cystine/glutamate transporter
Sources

Homo sapiens ncbi:9606

Specimen Preparationvitrification
MicroscopeFEI TITAN KRIOS (300 kV)
DetectorGATAN K3 BIOQUANTUM (6k x 4k)
Electron Dose59.1 (e/sq. Å)
Number of Particles300221
Imposed SymmetryC1

Details: postprocessed

Map File Size131 Mbytes
Voxel Dimensions (Å)0.83199996 x 0.83199996 x 0.83199996
Map Dimensions (voxels) 320 x 320 x 320
Map Data Type IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
Density StatisticsMin -1.044Max 2.475Avg -0.002Std 0.046
Recommended Contour Level0.4 (8.7 σ)
Mol*3DViewer Map Visual Analysis @ EMDB
Header Metadataemd-13267.xml emd-13267.cif.gz
Primary Mapemd_13267.map.gz (131 Mbytes)
Masksemd_13267_msk_1.map
Imagesemd_13267.png
FSC Curvesemd_13267_fsc.xml
Additional Maps
emd_13267_additional_1.map.gz
Half Maps
halfmap1emd_13267_half_map_1.map.gz
halfmap2emd_13267_half_map_2.map.gz
Fitted PDB7p9v


Current: files.wwpdb.org (USA)

wwPDB Map Validation Reportemd_13267_full_validation.pdf.gz
wwPDB Model Validation Report7p9v_full_validation.pdf.gz
View EMDB map entry EMD-13267: EMDB PDBj 3Dbionotes
View associated model PDB 7p9v: RCSB-PDB PDBe PDBj