|
1003
2002-06-26 RELEASED ON 2002-08-22
singleParticle 11.5Å
Solution structure of the E. coli 70S ribosome at
11.5 A resolution.
Gabashvili IS, Agrawal RK, Spahn CM, Grassucci RA,
Svergun DI, Frank J, Penczek P
Cell
100(5), 537-49 (2000 Mar 3) |
|
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1004
2002-08-27 RELEASED ON 2003-08-29
singleParticle 13Å
Ribosome interactions of aminoacyl-tRNA and
elongation factor Tu in the codon-recognition complex.
Stark H, Rodnina MV, Wieden HJ, Zemlin F,
Wintermeyer W, van Heel M
Nat
Struct Biol 9(11), 849-54 (2002 Nov) |
|
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1006..1010
2002-09-01 RELEASED ON 2003-09-26
singleParticle 11.3Å
A cryo-electron microscopic study of
ribosome-bound termination factor RF2.
Rawat UB, Zavialov AV, Sengupta J, Valle M,
Grassucci RA, Linde J, Vestergaard B, Ehrenberg M, Frank J
Nature
421(6918), 87-90 (2003 Jan 2) |
|
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1056
2003-09-22 RELEASED ON 2004-01-06
singleParticle 9Å
Incorporation of aminoacyl-tRNA into the ribosome
as seen by cryo-electron microscopy.
Valle M, Zavialov A, Li W, Stagg SM, Sengupta J,
Nielsen RC, Nissen P, Harvey SC, Ehrenberg M, Frank J
Nat
Struct Biol 10(11), 899-906 (2003 Nov) |
|
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1063
2003-12-19 RELEASED ON 2004-12-19
singleParticle 12.0Å
Structure of the signal recognition particle
interacting with the elongation-arrested ribosome.
Halic M, Becker T, Pool MR, Spahn CM, Grassucci
RA, Frank J, Beckmann R
Nature
427(6977), 808-14 (2004 Feb 26) |
|
|
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1067
2004-01-05 RELEASED ON 2005-01-06
singleParticle 11.7Å
Domain movements of elongation factor eEF2 and the
eukaryotic 80S ribosome facilitate tRNA translocation.
Spahn CM, Gomez-Lorenzo MG, Grassucci RA,
Jørgensen R, Andersen GR, Beckmann R, Penczek PA, Ballesta JP, Frank J
EMBO
J 23(5), 1008-19 (2004 Mar 10) |
|
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1068
2004-03-02 RELEASED ON 2004-04-28
singleParticle 13.4Å
Three-dimensional structures of translating
ribosomes by Cryo-EM.
Gilbert RJ, Fucini P, Connell S, Fuller SD,
Nierhaus KH, Robinson CV, Dobson CM, Stuart DI
Mol
Cell 14(1), 57-66 (2004 Apr 9) |
|
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1070..1073
2004-03-14 RELEASED ON 2004-04-28
singleParticle 13.4Å
Three-dimensional structures of translating
ribosomes by Cryo-EM.
Gilbert RJ, Fucini P, Connell S, Fuller SD,
Nierhaus KH, Robinson CV, Dobson CM, Stuart DI
Mol
Cell 14(1), 57-66 (2004 Apr 9) |
|
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1076
2004-03-10 RELEASED ON 2004-04-07
singleParticle 15.4Å
Structure of the 80S ribosome from Saccharomyces
cerevisiae--tRNA-ribosome and subunit-subunit interactions.
Spahn CM, Beckmann R, Eswar N, Penczek PA, Sali A,
Blobel G, Frank J
Cell
107(3), 373-86 (2001 Nov 2) |
|
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1077
2004-04-14 RELEASED ON 2005-04-14
singleParticle 12Å
Visualization of ribosome-recycling factor on the
Escherichia coli 70S ribosome: functional implications.
Agrawal RK, Sharma MR, Kiel MC, Hirokawa G, Booth
TM, Spahn CM, Grassucci RA, Kaji A, Frank J
Proc
Natl Acad Sci U S A 101(24), 8900-5 (2004 Jun 15) |
|
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1090..1093
2004-08-10 RELEASED ON 2004-11-10
singleParticle 20.3Å
Cryo-EM
visualization of a viral internal ribosome entry site bound to human
ribosomes: the IRES functions as an RNA-based translation factor.
Spahn CM, Jan E, Mulder A, Grassucci RA, Sarnow P,
Frank J
Cell
118(4), 465-75 (2004 Aug 20) |
|
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1110
2005-02-22 RELEASED ON 2005-07-05
singleParticle 18Å
Structural basis for the function of the ribosomal
L7/12 stalk in factor binding and GTPase activation.
Diaconu M, Kothe U, Schlünzen F, Fischer N, Harms
JM, Tonevitsky AG, Stark H, Rodnina MV, Wahl MC
Cell
121(7), 991-1004 (2005 Jul 1) |
|
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1138
2005-07-27 RELEASED ON 2006-07-27
singleParticle 15Å
Structure of the hepatitis C virus IRES bound to
the human 80S ribosome: remodeling of the HCV IRES.
Boehringer D, Thermann R, Ostareck-Lederer A,
Lewis JD, Stark H
Structure
13(11), 1695-706 (2005 Nov) |
|
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1143
2005-08-03 RELEASED ON 2006-06-13
singleParticle 14.9Å
Structure of the E. coli protein-conducting
channel bound to a translating ribosome.
Mitra K, Schaffitzel C, Shaikh T, Tama F, Jenni S,
Brooks CL, Ban N, Frank J
Nature
438(7066), 318-24 (2005 Nov 17) |
|
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1168..1169
2005-10-10 RELEASED ON 2006-10-10
singleParticle
ERj1p uses a universal ribosomal adaptor site to
coordinate the 80S ribosome at the membrane.
Blau M, Mullapudi S, Becker T, Dudek J, Zimmermann
R, Penczek PA, Beckmann R
Nat
Struct Mol Biol 12(11), 1015-6 (2005 Nov) |
|
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1172..1173
2005-09-14 RELEASED ON 2006-10-27
singleParticle 11.5Å
Conformational transition of initiation factor 2
from the GTP- to GDP-bound state visualized on the ribosome.
Myasnikov AG, Marzi S, Simonetti A, Giuliodori AM,
Gualerzi CO, Yusupova G, Yusupov M, Klaholz BP
Nat
Struct Mol Biol 12(12), 1145-9 (2005 Dec) |
|
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1184..1185
2006-01-31 RELEASED ON 2006-05-09
singleParticle 12.8Å
Interactions of the release factor RF1 with the
ribosome as revealed by cryo-EM.
Rawat U, Gao H, Zavialov A, Gursky R, Ehrenberg M,
Frank J
J Mol
Biol 357(4), 1144-53 (2006 Apr 7) |
|
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1197..1199
2006-02-28 RELEASED ON 2006-05-11
singleParticle 16.2Å
A mechanical explanation of RNA pseudoknot
function in programmed ribosomal frameshifting.
Namy O, Moran SJ, Stuart DI, Gilbert RJ, Brierley I
Nature
441(7090), 244-7 (2006 May 11) |
|
|
1211..1212
2006-03-28 RELEASED ON 2006-06-01
singleParticle 34Å
Hrr25-dependent phosphorylation state regulates
organization of the pre-40S subunit.
Schäfer T, Maco B, Petfalski E, Tollervey D,
Böttcher B, Aebi U, Hurt E
Nature
441(7093), 651-5 (2006 Jun 1) |
|
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1233
2006-06-27 RELEASED ON 2006-10-12
singleParticle 9.9Å
Structure of eEF3 and the mechanism of transfer
RNA release from the E-site.
Andersen
CB, Becker T, Blau M, Anand M, Halic M, Balar B, Mielke T, Boesen T,
Pedersen JS, Spahn CM, Kinzy TG, Andersen GR, Beckmann R
Nature
443(7112), 663-8 (2006 Oct 12) |
|
|
1250..1251
2006-07-28 RELEASED ON 2008-07-29
singleParticle 15.5Å
Structure of the E. coli signal recognition
particle bound to a translating ribosome.
Schaffitzel C, Oswald M, Berger I, Ishikawa T,
Abrahams JP, Koerten HK, Koning RI, Ban N
Nature
444(7118), 503-6 (2006 Nov 23) |
|
|
1261..1264
2006-08-21 RELEASED ON 2007-08-28
singleParticle 9.5Å
Following the signal sequence from ribosomal
tunnel exit to signal recognition particle.
Halic M, Blau M, Becker T, Mielke T, Pool MR, Wild
K, Sinning I, Beckmann R
Nature
444(7118), 507-11 (2006 Nov 23) |
|
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1285
2006-10-31 RELEASED ON 2007-10-31
singleParticle 7.3Å
Structure of the ribosome-bound cricket paralysis
virus IRES RNA.
Schüler M, Connell SR, Lescoute A, Giesebrecht J,
Dabrowski M, Schroeer B, Mielke T, Penczek PA, Westhof E, Spahn CM
Nat
Struct Mol Biol 13(12), 1092-6 (2006 Dec) |
|
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1302
2006-11-29 RELEASED ON 2007-06-22
singleParticle 15.5Å
RF3 induces ribosomal conformational changes
responsible for dissociation of class I release factors.
Gao H, Zhou Z, Rawat U, Huang C, Bouakaz L, Wang
C, Cheng Z, Liu Y, Zavialov A, Gursky R, Sanyal S, Ehrenberg M, Frank
J, Song H
Cell
129(5), 929-41 (2007 Jun 1) |
|
|
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1310
2006-12-12 RELEASED ON 2007-06-12
singleParticle 11.8Å
Scaffolding as an organizing principle in
trans-translation. The roles of small protein B and ribosomal protein
S1.
Gillet R, Kaur S, Li W, Hallier M, Felden B, Frank
J
J
Biol Chem 282(9), 6356-63 (2007 Mar 2) |
|
|
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1312
2006-12-13 RELEASED ON 2007-12-14
singleParticle 13.1Å
Scaffolding as an organizing principle in
trans-translation. The roles of small protein B and ribosomal protein
S1.
Gillet R, Kaur S, Li W, Hallier M, Felden B, Frank
J
J
Biol Chem 282(9), 6356-63 (2007 Mar 2) |
|
|
1315
2007-01-18 RELEASED ON 2008-01-19
singleParticle 7.3Å
Structural basis for interaction of the ribosome
with the switch regions of GTP-bound elongation factors.
Connell
SR, Takemoto C, Wilson DN, Wang H, Murayama K, Terada T, Shirouzu M,
Rost M, Schüler M, Giesebrecht J, Dabrowski M, Mielke T, Fucini P,
Yokoyama S, Spahn CM
Mol
Cell 25(5), 751-64 (2007 Mar 9) |
|
|
|
1342..1345
2007-03-20 RELEASED ON 2007-06-12
singleParticle 11.3Å
Structures of modified eEF2 80S ribosome complexes
reveal the role of GTP hydrolysis in translocation.
Taylor DJ, Nilsson J, Merrill AR, Andersen GR,
Nissen P, Frank J
EMBO
J 26(9), 2421-31 (2007 May 2) |
|
|
1346..1349
2007-03-27 RELEASED ON 2007-06-06
singleParticle 21Å
The eukaryotic translation initiation factors eIF1
and eIF1A induce an open conformation of the 40S ribosome.
Passmore LA, Schmeing TM, Maag D, Applefield DJ,
Acker MG, Algire MA, Lorsch JR, Ramakrishnan V
Mol
Cell 26(1), 41-50 (2007 Apr 13) |
|
|
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1369..1370
2007-06-01 RELEASED ON 2008-01-07
singleParticle 18.4Å
Progression of the ribosome recycling factor
through the ribosome dissociates the two ribosomal subunits.
Barat C, Datta PP, Raj VS, Sharma MR, Kaji H, Kaji
A, Agrawal RK
Mol
Cell 27(2), 250-61 (2007 Jul 20) |
|
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1391
2007-06-22 RELEASED ON 2007-11-15
singleParticle 10Å
Structured mRNAs regulate translation initiation
by binding to the platform of the ribosome.
Marzi S, Myasnikov AG, Serganov A, Ehresmann C,
Romby P, Yusupov M, Klaholz BP
Cell
130(6), 1019-31 (2007 Sep 21) |
|
|
1395
2007-07-27 RELEASED ON 2007-08-02
singleParticle 12.8Å
Incorporation of aminoacyl-tRNA into the ribosome
as seen by cryo-electron microscopy.
Valle M, Zavialov A, Li W, Stagg SM, Sengupta J,
Nielsen RC, Nissen P, Harvey SC, Ehrenberg M, Frank J
Nat
Struct Biol 10(11), 899-906 (2003 Nov) |
|
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1417
2007-08-31 ON HOLD singleParticle
9.4Å
Cryo-EM
study of the spinach chloroplast ribosome reveals the structural and
functional roles of plastid-specific ribosomal proteins.
Sharma MR, Wilson DN, Datta PP, Barat C,
Schluenzen F, Fucini P, Agrawal RK
Proc
Natl Acad Sci U S A 104(49), 19315-20 (2007 Dec 4) |
|
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1430
2007-09-24 RELEASED ON 2007-12-12
singleParticle 9.1Å
Specific interaction between EF-G and RRF and its
implication for GTP-dependent ribosome splitting into subunits.
Gao N, Zavialov AV, Ehrenberg M, Frank J
J Mol
Biol 374(5), 1345-58 (2007 Dec 14) |
|
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1480
2008-02-24 RELEASED ON 2009-03-31
singleParticle 8.7Å
Structure of the mammalian 80S ribosome at 8.7 A
resolution.
Chandramouli P, Topf M, Ménétret JF, Eswar N,
Cannone JJ, Gutell RR, Sali A, Akey CW
Structure
16(4), 535-48 (2008 Apr) |
|
|
1484
2008-02-26 RELEASED ON 2009-05-29
singleParticle 9.6Å
Ribosome binding of a single copy of the SecY
complex: implications for protein translocation.
Ménétret
JF, Schaletzky J, Clemons WM, Osborne AR, Skånland SS, Denison C, Gygi
SP, Kirkpatrick DS, Park E, Ludtke SJ, Rapoport TA, Akey CW
Mol
Cell 28(6), 1083-92 (2007 Dec 28) |
|
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1499
2008-04-04 RELEASED ON 2009-05-29
singleParticle 19Å
Molecular mechanism and structure of Trigger
Factor bound to the translating ribosome.
Merz F, Boehringer D, Schaffitzel C, Preissler S,
Hoffmann A, Maier T, Rutkowska A, Lozza J, Ban N, Bukau B, Deuerling E
EMBO
J 27(11), 1622-32 (2008 Jun 4) |
|
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1524
2008-06-10 RELEASED ON 2009-04-01
singleParticle 10.9Å
A new tRNA intermediate revealed on the ribosome
during EF4-mediated back-translocation.
Connell SR, Topf M, Qin Y, Wilson DN, Mielke T,
Fucini P, Nierhaus KH, Spahn CM
Nat
Struct Mol Biol 15(9), 910-5 (2008 Sep) |
|
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1528
2008-06-23 RELEASED ON 2009-04-15
singleParticle 8.7Å
Single copies of Sec61 and TRAP associate with a
nontranslating mammalian ribosome.
Ménétret JF, Hegde RS, Aguiar M, Gygi SP, Park E,
Rapoport TA, Akey CW
Structure
16(7), 1126-37 (2008 Jul) |
|
|
1540..1541
2008-08-12 RELEASED ON 2009-08-26
singleParticle 10.5Å
Visualization of the hybrid state of tRNA binding
promoted by spontaneous ratcheting of the ribosome.
Agirrezabala X, Lei J, Brunelle JL, Ortiz-Meoz RF,
Green R, Frank J
Mol
Cell 32(2), 190-7 (2008 Oct 24) |
|
|
|
1564..1565
2008-09-29 ON HOLD singleParticle 12Å
Recognition of aminoacyl-tRNA: a common molecular
mechanism revealed by cryo-EM.
Li W, Agirrezabala X, Lei J, Bouakaz L, Brunelle
JL, Ortiz-Meoz RF, Green R, Sanyal S, Ehrenberg M, Frank J
EMBO
J 27(24), 3322-31 (2008 Dec 17) |
|
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1582
2008-11-07 RELEASED ON 2009-06-11
singleParticle 30Å
The native 3D organization of bacterial polysomes.
Brandt F, Etchells SA, Ortiz JO, Elcock AH, Hartl
FU, Baumeister W
Cell
136(2), 261-71 (2009 Jan 23) |
|
|
1615..1616
2009-04-23 ON HOLD singleParticle
14.4Å
YidC and Oxa1 form dimeric insertion pores on the
translating ribosome.
Kohler R, Boehringer D, Greber B,
Bingel-Erlenmeyer R, Collinson I, Schaffitzel C, Ban N
Mol
Cell 34(3), 344-53 (2009 May 15) |
|
|
5015..5017
2008-06-20 RELEASED ON 2009-05-05
singleParticle 12.6Å
Visualization of the eEF2-80S ribosome
transition-state complex by cryo-electron microscopy.
Sengupta J, Nilsson J, Gursky R, Kjeldgaard M,
Nissen P, Frank J
J Mol
Biol 382(1), 179-87 (2008 Sep 26) |
|
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5030
2008-10-30 RELEASED ON 2009-05-05
singleParticle 6.4Å
GTPase activation of elongation factor EF-Tu by
the ribosome during decoding.
Schuette
JC, Murphy FV, Kelley AC, Weir JR, Giesebrecht J, Connell SR, Loerke J,
Mielke T, Zhang W, Penczek PA, Ramakrishnan V, Spahn CM
EMBO
J , (2009 Feb 19) |
|
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5036
2008-12-01 RELEASED ON 2009-05-05
singleParticle 6.7Å
Flexible fitting of atomic structures into
electron microscopy maps using molecular dynamics.
Trabuco LG, Villa E, Mitra K, Frank J, Schulten K
Structure
16(5), 673-83 (2008 May) |
|
|
5041..5047
2009-01-08 RELEASED ON 2009-09-04
singleParticle 24Å
Survey of large protein complexes in D. vulgaris
reveals unexpected structural diversity
Han
BG, Dong M, Liu H, Camp L, Geller J, Singer M, Hazen TC, Choi M,
Witkowska HE, Ball DA, Typke D, Downing KH, Shatsky M, Brenner SE,
Chandonia JM, Biggin MD, Glaeser RM
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